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Prenatal Vitamins and Other Benefits of Folic Acidwaist trainer
We all know that folic acid for pregnancy is great. That’s why folic acid is one of the primary nutrients in prenatal vitamins. However, folates and folic acid do much more for the body. Below is an excerpt from an nutrition newsletter that I receive every day. Occasionally it talks about pregnancy nutrition, but for the most part it reviews nutrition industry news. Today however, there was a noteworthy article about a study that indicates that folic acid may also help reduce the risk of colorectal cancers. If have reprinted the article in its entirety below; here is a link to the actual post The article does also mention the benefit of folic acid for prenatal development, but the focus is primarily on the new body of science around folic acid as a nutrient.formexplode
Increased intakes of folate from the diet may reduce a woman’s risk of colorectal cancer by about 50 per cent, according to new findings from Korea.turbo max blue predaj
The highest intakes of folate, a B-vitamin found in green leafy vegetables, chick peas and lentils, were associated with a 66, and 70 per cent reduction in a woman’s risk of cancers of the colon and rectum, respectively, report researchers in the European Journal of Clinical Nutrition (EJCN).
However, men did not benefit from the vitamin, said the researchers from Korea’s National Cancer Center, Hallym University, Inha University College of Medicine, and Seoul National University.
The study adds to an ever-growing body of case-control and prospective cohort studies have reported that increased intakes of folate may reduce the risk of colorectal cancer by 40 to 60 per cent.
An overwhelming body of evidence links has linked folate deficiency in early pregnancy to increased risk of neural tube defects (NTD) – most commonly spina bifida and anencephaly – in infants.
This connection led to the 1998 introduction of public health measures in the US and Canada, where all grain products are fortified with folic acid – the synthetic, bioavailable form of folate.
Preliminary evidence indicates that the measure is having an effect with a reported 15 to 50 per cent reduction in NTD incidence. In Chile, the measure has been associated with a 40 per cent reduction in NTDs. Parallel measures in European countries, including the UK and Ireland, are still on the table.
Over 30 case-control and prospective cohort studies have reported colorectal cancer risk reduction associated to the vitamin. Similar risk reductions have also been reported for the lesion that precedes the cancer, the adenomatous polyp. However, some studies have linked folic acid intakes to an increased risk of the disease.
A review paper published in the April issue of Nutrition Reviews by Joel Mason from USDA Human Nutrition Research Center on Aging at Tufts University addressed the potential Janus effect of folate on colorectal health.
“Under most circumstances, adequate intake of folate appears to assume the role of a protective agent against cancer, most notably colorectal cancer,” wrote Dr Mason. “However, in select circumstances in which an individual who harbours a pre-cancerous or cancerous tumour consumes too much folic acid, the additional amounts of folate may instead facilitate the promotion of cancer.”
The complex links between folate and cancer have created a “global dilemma”, said Dr Mason, with regards to instituting folic acid fortification programs in other countries.
The Korean researchers analysed data obtained from 596 men and women with colorectal cancer, and compared this to data from 509 people free of the disease. All the participants were aged between 30 and 79.
According to the EJCN report, the overall data showed that the highest levels of folate intake were linked to a 53, 58 and 52 per cent reduced risk of colorectal, colon, and rectal cancer, respectively for all the people studied.
However, when the researchers focussed on the sex of the participants, only women were found to benefit, with the highest levels of folate intake were linked to a 64, 66, and 70 per cent reduced risk of colorectal, colon, and rectal cancer, respectively.
“We found a statistically significant relationship between higher dietary folate intake and reduced risk of CRC, colon cancer and rectal cancer in women,” concluded the researchers.
A possible explanation for the contradictory results of studies with the vitamin and colorectal cancer may be the difference between the synthetic and natural forms of the vitamin. “The fact that folic acid, which is not a naturally occurring form of the vitamin, is used by food and pharmaceutical industries for fortification and supplementation is potentially of importance,” wrote Tufts University’s Mason in Nutrition Reviews.
On passage through the intestinal wall, folic acid is converted to 5-methyltetrahydrofolate, the naturally circulating form of folate. However, some studies have suggested that oral doses of folic acid in high doses may overwhelm this conversion pathway, leading to measurable levels of folic acid in the blood.
“There has been some concern that this oxidized, non-substituted form of folate might feasibly be detrimental because it is not a naturally occurring co-enzymatic form of the vitamin,” he added.
Source: European Journal of Clinical Nutrition
Published online ahead of print, doi:10.1038/ejcn.2009.37“Folate intake and the risk of colorectal cancer in a Korean population”
Authors: J. Kim, D.H. Kim, B.H. Lee, S.H. Kang, H.J. Lee, S.Y. Lim, Y.K. Sun, Y.O. Ahn
Folic acid ‘protects baby hearts’ (news.bbc.co.uk)
Posted on July 7th, 2009 by Bloomen Nutrition No Comments »
Image by luc legay via Flickr
A lot has been happening behind the scenes this past couple of weeks. Okay, if you have been following our Twitter Feeds, it may not be so much behind the scenes. Regardless, we have been really busy. To bring you up to speed, we have spending time polishing our look, working on prenatal vitamin search engine optimization, and focusing on getting our fantastic chewable prenatal vitamins into more retail stores. It has been a busy time, but we all know that it will pay off.
If you separate our activities into online and offline, we have been busy working to search engine optimize our main site, Bloom’en Nutrition, and even received some recognition and a bit of help from the people over at Marketing Experiments. Hopefully with their good input, our site should show up in the top spots for some highly desirable search terms. We had some great success this morning with the search term Prenatal Vitamin.
In addition to the prenatal vitamin search activities, we have recently received in an order of our trade show bags and are working to create a promotion for many of our autoship customers so that they can get their hands on these great reusable shopping bags. They turned out really cute, with the Bloom’en orange as the main color and our logo in white. Be sure to visit our website periodically to see how you can get one of these cute little carry-alls.
To become more visible online, we also have a new Facebook page where you can tune in to see what our team is up to. We also have our MothersClick page and our presence on the Bump. We are also working on updating the backgrounds of our Twitter pages to make them a little more “Bloom’en” so keep an eye out for some subtle changes.
Off-line, we are working with a few retail distributors and courting a few large natural food retailers. Look for our tasty little chews in a store near you very soon.
Breaking: Facebook Username Landrush to Start June 13 at Midnight (insidefacebook.com)
Posted on June 30th, 2009 by Bloomen Nutrition No Comments »
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